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NA-921 (Bionetide™)

NA-921 (Bionetide)™is a small molecule drug that is in Phase 2/3 clinical trials for the treatment of Rett Syndrome.

How does NA-921 (Bionetide™) work?

NA-921 (Bionetide) can easily cross the blood brain barrier, so only a small dose of the drug is required to be effective. The drug shows the following properties:

* NA-921 exhibits neuroprotection

* NA-921 exhibits neurogenesis, i.e. ability to generate new neurons

* It has great bioavailability in the body

* It is very safe, with no toxicity observed

* It is available in oral formulation


PHASE 2/3 CLINICAL TRIALS of NA-921

To Study the Efficacy & Safety of Oral NA-921 (Bionetide) in Girls and Women with Rett Syndrome
ClinicalTrials.gov ID NCT06849973

A Randomized, Double-Blind, Placebo-Controlled, Phase 2/3 Study of NA-921 (Bionetide) for the Treatment of Girls and Women with Rett Syndrome

Primary Objective • To investigate the efficacy and safety of treatment with oral NA-921 (Bionetide) versus placebo in girls and women with Rett syndrome

Key Secondary Objective • To investigate the efficacy of treatment with oral NA-921 (Bionetide) versus placebo on ability to communicate in girls and women with Rett syndrome


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