A New Method for the Treatment of Alzheimer's Disease

New treatment for AD
  • The Drug: NA-831 is for the treatment of Alzheimer’s disease
  • The Clinical Stage: completed Phase 2A and is ready to launch a Phase 3
  • NA-831 is oral dosage, 30 mg once per day, no adverse effects

  • HOW DOES IT WORK?
    NA-831 is a new nanocatalyst discovered by Biomed reasearch team. It works in according to a concept of organcatalysis proposed by Drs. Benjamin List and David MacMillan, for which they were awarded the 2021 Nobel prize in chemistry.

    NA-831 facilitates the regeneration of new neurons to improve memory and cognitive functions for Alzheimer's patients

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    NA-831, a new Neurocatalyst that regenerates new neurons to improve cognition functions

    The hippocampus is essential for learning and memory formation and one of the first brain regions affected in the development of Alzheimer’s disease (AD). In the hippocampus, new neurons are generated throughout life via a process called adult hippocampal neurogenesis (AHN).

    In mild cognitive impairment (MCI) and mild to moderate AD (early AD), AHN is reduced suggesting that AHN impairment compromises hippocampal function. Accordingly, augmenting AHN could help prevent or slow cognitive decline in MCI and early AD.

    NA-831 restores neurogenesis by activating synaptic AMPA receptors, and increases the expression of BDNF (brain derived neurotrophic factor). BDNF is crucial in synaptic plasticity, learning and memory formation in the hippocampus.


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    Traneurocin NA-831 bottle
    Traneurocin (NA-831)

    Traneuroci™ or NA-831 provides neuroprotection and catalyzing the regeneration of new neurons. Oral 30 mg per day for patients with early onset of Alzheimer’s Disease. NA-831 is manufactured by NeuroActiva, a subsidiary of Biomed. 

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    Neurogenesis
    How does it work?

    In Alzheimer’s patients, the ability to regenerate new neurons in the hippocampus is impaired, causing memory loss and cognitive disorders. NA-831 facilitates neurogenesis restoring memory loss and improve cognitive functions.

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    clinical trials
    Research & Clinical Trials

    Biomed is conducting Phase 3 clinical trials of NA-831 for the treatment and prevention of Alzheimer’s disease. We also conduct Phase 2/3 trials of NA-831 in combination with Atazanavir, Remdesivir, and Dexaneurosone and Ivermectin for treating Covid-19

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    NA-704 injectable drug
    NA-704

    Vineurocin (NA-704) is an injectable drug, to regenerate new neurons, and reducting of muscular spasticity, a strong candidate for treatment of Alzheimer’s disease and Parkinson’s disease. NA-704 can be administered with the MICROS. NA-704 is in the Phase 1 safety studies.

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    MICROS
    MICROS™ Infusion System

    The MICROS is a controlled release infusion system which has been approved for marketing in the US. It is used for intravenous administration of injectable drugs. NA-704 can be administerd via the MICROS at home care settings. It is an accurate, safe and cost effective drug delivery system.

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    drug mixture
    NA-831 + Antiviral Drugs for Covid-19

    Combination therapy of NA-831 and an antiviral drugs such as Atazanavir, Remdesivir (Gilead Sciences) and anti-inflammatory such as Dexaneurosone and Ivermectin can enhance the effectiveness of the treatment of Covid-19.

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    Neurogenesis

    Neurogenesis and
    Alzheimer's Disease

    NA-831 restores neurogenesis by increasing the expression of BDNF (brain derived neurotrophic factor). NA-831 serves as a catalyst to restore neurogenesis in Alzheimer’s patients, with higher numbers of neuroblasts leading to improved cognitive function. Learn more

    Covid-19

    and Alzheimer's disease

    Covid-19 viruses can cross the blood brain barrier via infected vascular endothelial cells and/or infected leukocytes to damage the central nervous system.
    As a neuroprotective agent, NA-831 can protect the brain from Covid-19 infection. Learn more
    Covid-19- brain